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This event may represent a possible mechanism by which myelin phagocytosis results in a pro-inflammatory response and would explain the acquisition of the inflammatory role of microglia in later stages of the lesion

The authors declare that they have no conflicts and were not involved in the journal's review or decision regarding this manuscript

The menopausal transition is associated with a natural decline in estrogen and nitric oxide production, which can impair endothelial function[6] and reduce genital blood flowkey elements in arousal and sexual response

The result: anxious thoughts dial down and concentration sharpens, without sedation or dependency